Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023282 | 0.85 | KMT2A (0.47) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29811767 | 0.81 | KMT2A (0.44) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19252150 | 0.81 | KMT2A (0.44) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28246138 | 0.74 | HTR6 (0.52) | HTR6KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30958211 | 0.74 | MEN1 (0.45) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL17422100 | 0.74 | AGTR1 (0.41) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26380620 | 0.73 | MEN1 (0.41) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3241536 | 0.71 | HTR6 (0.61) | HTR6KMT2AMEN1ALDH1A1HTR2A | |
| SCHEMBL29687030 | 0.71 | HTR6 (0.61) | HTR6KMT2AMEN1ALDH1A1HTR2A | |
| SCHEMBL23144691 | 0.70 | HTR2A (0.46) | HTR6KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677722-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2023-02-03 | — | — | CN | disclosed |