Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 19/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30379442 | 0.89 | SYK (0.50) | ALKIGF1RCDK2 | |
| SCHEMBL28532459 | 0.85 | FGFR1 (0.49) | ALKIGF1RCDK2 | |
| SCHEMBL30379611 | 0.85 | FGFR1 (0.49) | ALKIGF1RCDK2 | |
| SCHEMBL21600758 | 0.84 | MAPK3 (0.54) | ALK | |
| SCHEMBL30379344 | 0.84 | MAPK3 (0.54) | ALK | |
| SCHEMBL21600782 | 0.84 | ALK (0.49) | ALKIGF1RCDK2 | |
| SCHEMBL28533769 | 0.83 | ALK (0.56) | ALKIGF1R | |
| SCHEMBL28909338 | 0.83 | ALK (0.55) | ALKIGF1R | |
| SCHEMBL28537291 | 0.81 | PLK1 (0.63) | ALKIGF1R | |
| SCHEMBL28546939 | 0.81 | TTK (0.43) | ALKIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |