Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 5/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | STAT1 | P42224 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299743 | 0.81 | RAB9A (0.53) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28847575 | 0.79 | CSF1R (0.43) | NPC1RAB9AALDH1A1TSHRMAPK1 | |
| SCHEMBL16536466 | 0.78 | POLB (0.47) | NPC1RAB9AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28299561 | 0.74 | NPC1 (0.49) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28299729 | 0.73 | NPC1 (0.46) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28301083 | 0.73 | CA1 (0.46) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28300981 | 0.73 | CCKAR (0.45) | RAB9AFABP3FABP4 | |
| SCHEMBL28299787 | 0.72 | NPC1 (0.47) | NPC1RAB9AALDH1A1MAPK1HPGD | |
| SCHEMBL28301021 | 0.72 | CA1 (0.55) | RAB9AFABP3FABP4 | |
| SCHEMBL19926970 | 0.70 | NPC1 (0.45) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |