Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.78 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289639 | 0.94 | SSTR5 (0.89) | SSTR5KCNH2PTGDR | |
| SCHEMBL10127153 | 0.94 | SSTR5 (0.85) | SSTR5KCNH2PTGDR | |
| SCHEMBL289597 | 0.90 | SSTR5 (0.76) | SSTR5KCNH2PTGDR | |
| SCHEMBL25900754 | 0.88 | SSTR5 (0.76) | SSTR5KCNH2PTGDR | |
| Acetic Acid SCHEMBL3718442 | 0.88 | SSTR5 (0.81) | SSTR5KCNH2PTGDR | |
| SCHEMBL299979 | 0.88 | SSTR5 (1.00) | SSTR5KCNH2PTGDR | |
| SCHEMBL25900728 | 0.87 | SSTR5 (0.74) | SSTR5KCNH2PTGDR | |
| SCHEMBL13076435 | 0.85 | SSTR5 (0.86) | SSTR5KCNH2PTGDR | |
| SCHEMBL289895 | 0.84 | SSTR5 (0.88) | SSTR5KCNH2PTGDR | |
| SCHEMBL10111581 | 0.84 | SSTR5 (0.72) | SSTR5KCNH2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427465-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20120041012-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME CORP. | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041012-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | SSTR5, SSTR2, GPR119 | SSTR5 1/4885KCNH2 1142/4885PTGDR 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.