Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28954559 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL28917890 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL28592236 | 0.88 | TSHR (0.44) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL28954577 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL7545464 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL28594191 | 0.87 | ADRA2A (0.46) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6993526 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL28592239 | 0.86 | ADRA2A (0.45) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL28590806 | 0.86 | ADRA2A (0.45) | SMN1; SMN2HTTHPGDALDH1A1MEN1 | |
| SCHEMBL28917361 | 0.85 | HTT (0.40) | SMN1; SMN2HTTHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703737-B | Hydroxypyridones compound and application thereof as antibiotic sensitizer for overcoming bacterial biomembrane resistance | 暨南大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-115703737-A | Hydroxypyridones compounds and application thereof as antibiotic sensitizer for overcoming drug resistance of bacterial biofilm | 暨南大学 | 2023-02-17 | — | — | CN | disclosed |