Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28592239 | 1.00 | ADRA2A (0.45) | ADRA2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28594191 | 0.99 | ADRA2A (0.46) | ADRA2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28917890 | 0.95 | SMN1; SMN2 (0.43) | ADRA2AHTTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28954559 | 0.91 | SMN1; SMN2 (0.41) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL28917361 | 0.88 | HTT (0.40) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL28586083 | 0.88 | ALDH1A1 (0.42) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL28954587 | 0.88 | ADRA2A (0.46) | ADRA2AHTTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28592236 | 0.86 | TSHR (0.44) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL28954580 | 0.86 | SMN1; SMN2 (0.43) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL28954523 | 0.84 | SMN1; SMN2 (0.43) | ADRA2AHTTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736155-B | ALA hybrid 3-hydroxypyridone derivative, and preparation method and application thereof | 浙江工业大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-113121423-B | ALA hybrid 3-hydroxypyridone derivative and preparation method and application thereof | 浙江工业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114736155-A | ALA hybrid 3-hydroxypyridone derivative and preparation method and application thereof | 浙江工业大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-113121423-A | ALA hybrid 3-hydroxypyridone derivative and preparation method and application thereof | 浙江工业大学 | 2021-07-16 | — | — | CN | disclosed |