Biphenyl

Biphenyl

SCHEMBL28955867

CCC[N+](C)(CCC)CCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HPGD P15428 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
DNM1 Q05193 2/20 0.39
MAPT P10636 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TP53 P04637 2/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 3/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
SLC22A3 O75751 1/20 0.37
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28460813 0.98 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2L3MBTL1HPGDCHRNB2
Tributylmethylammonium SCHEMBL28955744 0.86 DNM1 (0.46) ALDH1A1SMN1; SMN2L3MBTL1HPGDCHRNB2
SCHEMBL7549490 0.84 DNM1 (0.36) ALDH1A1SMN1; SMN2CHRNB2CHRNB4CHRNA3
Tributylmethylammonium SCHEMBL28463343 0.84 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2L3MBTL1HPGDCHRNB2
Benzene SCHEMBL27744734 0.81 SLC22A1 (0.39) SMN1; SMN2DNM1MEN1KMT2ATP53
Benzene SCHEMBL27744740 0.81 SLC22A1 (0.39) ALDH1A1SMN1; SMN2DNM1MEN1KMT2A
Biphenyl SCHEMBL967556 0.78 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2L3MBTL1HPGDMAPT
SCHEMBL19244146 0.76 DNM1 (0.55) ALDH1A1SMN1; SMN2CHRNB4CHRNA3CHRNA7
SCHEMBL5944712 0.76 DNM1 (0.55) ALDH1A1SMN1; SMN2CHRNB4CHRNA3CHRNA7
Styrene SCHEMBL28189765 0.76 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2HPGDCHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732587-B Abamebactam intermediate compound gemini quaternary ammonium disulfonate and preparation method thereof 北京耀诚惠仁科技有限公司 2022-11-25 CN claimed