Phosphoric Acid

Phosphoric Acid

SCHEMBL28956255

N.N.N.N.O=C(O)C(O)CCl.O=P(O)(O)O

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.46
PGK2 P07205 1/20 0.46
OR51E2 Q9H255 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
TET2 Q6N021 6/20 0.37
KDM4A O75164 2/20 0.37
KDM4C Q9H3R0 2/20 0.37
KDM2A Q9Y2K7 2/20 0.37
TET3 O43151 2/20 0.37
TET1 Q8NFU7 1/20 0.34
PGD P52209 1/20 0.34
GPR84 Q9NQS5 3/20 0.32
FOLH1 Q04609 2/20 0.32
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28661856 1.00 PGK1 (0.46) PGK1PGK2OR51E2SMN1; SMN2TET2
Phosphoric Acid SCHEMBL28661858 1.00 PGK1 (0.46) PGK1PGK2OR51E2SMN1; SMN2TET2
Ammonia Solution, Strong SCHEMBL28639737 0.89
SCHEMBL5174260 0.87
SCHEMBL1406067 0.87
SCHEMBL574040 0.87
SCHEMBL28990425 0.84
SCHEMBL28482845 0.84
SCHEMBL27690428 0.81
Phosphoric Acid SCHEMBL29099337 0.75 PGK1 (0.32) PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113600097-B Preparation method of asymmetric gemini imidazoline phosphate surfactant 上海发凯化工有限公司 2023-02-14 CN disclosed