Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | CFTR | P13569 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478064 | 1.00 | MAPT (0.69) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL19032095 | 0.81 | CFTR (1.00) | CFTR | |
| SCHEMBL29478065 | 0.81 | CFTR (1.00) | CFTR | |
| SCHEMBL19448879 | 0.81 | MAPT (1.00) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL19032814 | 0.81 | CFTR (0.73) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL29497994 | 0.81 | CFTR (0.73) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL19046548 | 0.78 | CFTR (0.85) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL19032808 | 0.78 | CFTR (0.75) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL28362560 | 0.77 | ALDH1A1 (0.62) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL19032864 | 0.76 | CFTR (0.82) | MAPTMEN1KMT2ARAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710233-A | Modulators of CFTR and methods of use thereof | 加利福尼亚大学董事会 | 2023-02-24 | — | — | CN | disclosed |