Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | GSR | P00390 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448409 | 0.83 | MAPT (0.71) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL28694505 | 0.81 | MAPT (0.68) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL29478064 | 0.81 | MAPT (0.69) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL28957306 | 0.81 | MAPT (0.69) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL221991 | 0.78 | MAPT (0.63) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL14006985 | 0.78 | ALDH1A1 (1.00) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL7817360 | 0.77 | CYP3A4 (0.62) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL28516529 | 0.75 | KDM4E (0.82) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL30139977 | 0.75 | KDM4E (0.82) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL31448360 | 0.73 | ALDH1A1 (0.77) | MAPTRAB9AHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969699-B2 | Cancer cell growth inhibitor, anticancer agent, and method for screening same, as well as novel compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-05-15 | — | — | US | disclosed |
| US-9969699-B2 | Cancer cell growth inhibitor, anticancer agent, and method for screening same, as well as novel compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-05-15 | — | — | US | disclosed |
| US-20170291879-A1 | Cancer Cell Growth Inhibitor, Anticancer Agent, and Method for Screening Same, as well as Novel Compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-10-12 | — | — | US | disclosed |
| US-20170291879-A1 | Cancer Cell Growth Inhibitor, Anticancer Agent, and Method for Screening Same, as well as Novel Compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291879-A1 | Cancer Cell Growth Inhibitor, Anticancer Agent, and Method for Screening Same, as well as Novel Compound | EGFR, MKI67, ERBB2 | MAPT 4545/4885RAB9A 751/4885HTT 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.