Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.63 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.63 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160982 | 1.00 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL25192964 | 0.94 | POLB (0.65) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL30416216 | 0.94 | POLB (0.65) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL25845597 | 0.79 | MAPT (0.74) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL4875099 | 0.78 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL25374924 | 0.78 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL23092548 | 0.78 | MAPT (0.67) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL2793032 | 0.78 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL25372739 | 0.78 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3POLB | |
| SCHEMBL12182170 | 0.78 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |