Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28156609 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL28313467 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL28879046 | 0.83 | ALDH1A1 (0.71) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL28878993 | 0.83 | GRM2 (0.56) | ALDH1A1MAPTGRM2DHODHCNR2 | |
| SCHEMBL28879012 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL22292210 | 0.81 | KDM4E (0.62) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL28234814 | 0.77 | ALDH1A1 (1.00) | ALDH1A1NPSR1KDM4EMAPTMEN1 | |
| SCHEMBL30064613 | 0.77 | ALDH1A1 (0.65) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL14409758 | 0.77 | ALDH1A1 (0.65) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL18698068 | 0.77 | ALDH1A1 (0.85) | ALDH1A1LMNANPSR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249689-A | Synthetic method of benzoyl quinoline compound | 温州大学 | 2022-03-29 | — | — | CN | disclosed |