Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ACACA | Q13085 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559497 | 0.87 | PLA2G2A (0.62) | ALDH1A1PLA2G2AMTNR1AMTNR1BAURKA | |
| SCHEMBL28156608 | 0.85 | PLA2G2A (0.53) | ALDH1A1PLA2G2ANQO2MTNR1AMTNR1B | |
| SCHEMBL28958166 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CNR2KMT2AKDM4EMEN1 | |
| SCHEMBL28879046 | 0.80 | ALDH1A1 (0.71) | ALDH1A1CNR2KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28878993 | 0.80 | GRM2 (0.56) | ALDH1A1CNR2MAPTGRM2 | |
| SCHEMBL30064616 | 0.79 | KDM4E (0.75) | ALDH1A1PLA2G2ANQO2AURKAAURKB | |
| SCHEMBL28350370 | 0.79 | KDM4E (0.75) | ALDH1A1PLA2G2ANQO2AURKAAURKB | |
| SCHEMBL28494948 | 0.77 | AURKA (0.57) | ALDH1A1PLA2G2ANQO2AURKAAURKB | |
| SCHEMBL28491584 | 0.77 | GRM2 (0.57) | ALDH1A1PLA2G2AKMT2AKDM4EMEN1 | |
| SCHEMBL28155979 | 0.77 | RAB9A (0.53) | ALDH1A1PLA2G2AMTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249689-A | Synthetic method of benzoyl quinoline compound | 温州大学 | 2022-03-29 | — | — | CN | disclosed |