SCHEMBL28958238

SCHEMBL28958238

NCc1ccc(Br)c(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.43
LOXL2 Q9Y4K0 5/20 0.42
ABAT P80404 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
PNMT P11086 1/20 0.39
ENPP2 Q13822 1/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
ST14 Q9Y5Y6 1/20 0.39
CYP2A6 P11509 1/20 0.39
MAPT P10636 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875339 1.00 HRH3 (0.43) HRH3LOXL2ABATCA1CA2
SCHEMBL5705931 0.80 TAAR1 (0.56) CA1CA2PNMTCA12CA4
SCHEMBL13443566 0.80 HRH3 (0.40) HRH3LOXL2ABATCA1CA2
SCHEMBL30496702 0.80 TAAR1 (0.56) CA1CA2PNMTCA12CA4
SCHEMBL11441801 0.80 LOXL2 (0.44) HRH3LOXL2ABATCA1CA2
SCHEMBL1363230 0.78 CSNK2A1 (0.46) HRH3LOXL2PNMTCYP2A6TAAR1
SCHEMBL3400966 0.78 KDM4E (0.47) HRH3LOXL2ABATCA1CA2
SCHEMBL3398586 0.78 HRH3 (0.39) HRH3LOXL2ABATCA1CA2
SCHEMBL51845 0.78 KDM4E (0.47) HRH3LOXL2ABATCA1CA2
SCHEMBL5441282 0.78 ALOX15 (0.50) ABATCA1CA2ENPP2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed