Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27531090 | 0.94 | LMNA (0.62) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL28300132 | 0.85 | LMNA (0.59) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL27990624 | 0.82 | LMNA (0.56) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL3399482 | 0.80 | LMNA (0.71) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL11652408 | 0.79 | LMNA (1.00) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL7706117 | 0.79 | LMNA (1.00) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL10482239 | 0.79 | LMNA (1.00) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL11252224 | 0.79 | LMNA (1.00) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL8580358 | 0.79 | LMNA (1.00) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5065665 | 0.79 | LMNA (1.00) | LMNAALOX15HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115555575-B | Method for preparing nano cobalt particles by using thermal spraying method | 安徽格派锂电循环科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115555575-A | Method for preparing nano cobalt particles by utilizing thermal spraying method | 安徽格派锂电循环科技有限公司 | 2023-01-03 | — | — | CN | disclosed |