Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919367 | 0.76 | MEN1 (0.58) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL15709294 | 0.76 | MEN1 (0.58) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28881631 | 0.76 | PTGS1 (0.49) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28880855 | 0.76 | MEN1 (0.48) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL20390494 | 0.74 | ALDH1A1 (0.60) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28880810 | 0.73 | HPGD (0.61) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL13530383 | 0.73 | MEN1 (0.43) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL24326253 | 0.71 | MAPT (0.52) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL24997419 | 0.71 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8996846 | 0.70 | SMN1; SMN2 (0.51) | MAPTALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160285-A | Thioamides ALDH 2 Agonist, preparation method and application | 云南大学 | 2022-10-11 | — | — | CN | disclosed |