Benzoic Acid

Benzoic Acid

SCHEMBL28958510

C#Cc1ccc(N)cc1.O=C(O)c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
DAO P14920 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
MAPT P10636 2/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
SRD5A2 P31213 1/20 0.45
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
TP53 P04637 1/20 0.39
PBRM1 Q86U86 1/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
PARP1 P09874 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28958517 0.92 TSHR (0.48) TSHRDAONAPRTMAPTCES2
Benzoic Acid SCHEMBL16418108 0.86 TSHR (0.64) TSHRDAONAPRTMAPTCES2
Benzoic Acid SCHEMBL27308628 0.84 TSHR (0.74) TSHRDAONAPRTMAPTCES2
Terephthalic Acid SCHEMBL27838889 0.82 TSHR (0.56) TSHRDAONAPRTCES2CES1
SCHEMBL40299 0.82 TSHR (0.60) TSHRDAONAPRTCES2CES1
Aminobenzoic Acid SCHEMBL5058591 0.82 TSHR (0.70) TSHRDAONAPRTMAPTCES2
Hydrochloric Acid SCHEMBL2707678 0.80 TSHR (0.57) TSHRDAONAPRTCES2CES1
SCHEMBL160187 0.80 TSHR (0.57) TSHRDAONAPRTCES2CES1
SCHEMBL21324536 0.80 TSHR (0.74) TSHRDAONAPRTMAPTCES2
Benzoic Acid SCHEMBL3477053 0.80 TSHR (0.74) TSHRDAONAPRTMAPTCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115589736-A Perovskite composite layer and solar cell 嘉庚创新实验室 2023-01-10 CN claimed
CN-115589736-A Perovskite composite layer and solar cell 嘉庚创新实验室 2023-01-10 CN disclosed