Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413144 | 0.91 | KDM4C (0.40) | HRH3PABPC1KDM4CKDM4EALDH1A1 | |
| SCHEMBL17760501 | 0.73 | SCN9A (0.37) | HRH3 | |
| SCHEMBL3759484 | 0.72 | DPP4 (0.32) | HRH3 | |
| SCHEMBL28965124 | 0.70 | DRD2 (0.44) | HRH3PABPC1USP2ACHECXCR4 | |
| SCHEMBL28958743 | 0.70 | PDE10A (0.45) | HRH3PABPC1CXCR4HTTKDM4E | |
| SCHEMBL31238944 | 0.69 | CXCR4 (0.69) | HRH3PABPC1USP2ACHECXCR4 | |
| SCHEMBL8778016 | 0.69 | HPGD (0.55) | HRH3USP2CXCR4KDM4EALDH1A1 | |
| SCHEMBL5863593 | 0.69 | HPGD (0.55) | HRH3USP2CXCR4KDM4EALDH1A1 | |
| SCHEMBL18884481 | 0.67 | — | — | |
| SCHEMBL28958765 | 0.67 | CYP2D6 (0.41) | HRH3PABPC1USP2ACHECXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264901-B | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-113264901-A | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2021-08-17 | — | — | CN | disclosed |