Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958743 | 0.81 | PDE10A (0.45) | DRD2DRD4DRD3HTTHRH3 | |
| SCHEMBL8808928 | 0.80 | GFER (0.56) | DRD2DRD4DRD3ACHEHTT | |
| SCHEMBL28958765 | 0.77 | CYP2D6 (0.41) | DRD2DRD4DRD3ACHEHTT | |
| SCHEMBL15104529 | 0.77 | DRD2 (0.43) | DRD2DRD4DRD3ACHEGLA | |
| SCHEMBL28958741 | 0.73 | DRD2 (0.52) | DRD2DRD4DRD3HTTHRH3 | |
| SCHEMBL31238944 | 0.70 | CXCR4 (0.69) | ACHEGLAHTTNPSR1POLB | |
| SCHEMBL28958746 | 0.70 | HRH3 (0.43) | ACHEGLAHTTNPSR1POLB | |
| SCHEMBL15104610 | 0.70 | DRD2 (0.40) | DRD2DRD4DRD3ACHEOPRL1 | |
| SCHEMBL15219310 | 0.69 | PABPC1 (0.45) | HTTPOLBHRH3USP2PABPC1 | |
| SCHEMBL29986167 | 0.68 | LMNA (0.42) | ACHEHTTHRH3USP2PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264901-B | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-113264901-A | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2021-08-17 | — | — | CN | disclosed |