Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 8/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28092086 | 1.00 | CA2 (0.46) | CA2CA1GRIK1GRIK2FAAH | |
| SCHEMBL22160006 | 0.98 | CA2 (0.47) | CA2CA1GRIK1GRIK2FAAH | |
| SCHEMBL27892175 | 0.94 | CA2 (0.53) | CA2CA1FAAHCES1CES2 | |
| SCHEMBL22230486 | 0.81 | S1PR2 (0.42) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL27860089 | 0.80 | S1PR2 (0.40) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL6628807 | 0.79 | CA2 (0.50) | CA2CA1GRIK1GRIK2CES2 | |
| SCHEMBL7095586 | 0.78 | CA2 (0.52) | CA2CA1GRIK1GRIK2ZDHHC7 | |
| Trifluoroacetic Acid SCHEMBL6627804 | 0.76 | CA2 (0.65) | CA2CA1GRIK1GRIK2FAAH | |
| SCHEMBL3235440 | 0.76 | CA2 (0.68) | CA2CA1GRIK1GRIK2MAPT | |
| SCHEMBL20746502 | 0.76 | CA2 (0.68) | CA2CA1GRIK1GRIK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873069-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115707711-A | Peptide amide compound, pharmaceutically acceptable salt, stereoisomer and application thereof | 天地恒一制药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-115707712-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |