Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947807 | 0.90 | HMGB1 (0.47) | HMGB1CXCL12PTGS1PTGS2RXRA | |
| SCHEMBL27463635 | 0.85 | HMGB1 (0.49) | HMGB1CXCL12PTGS1PTGS2RXRA | |
| SCHEMBL27816873 | 0.84 | HMGB1 (0.52) | HMGB1CXCL12KDM4EMEN1KMT2A | |
| SCHEMBL13536253 | 0.82 | HMGB1 (0.46) | HMGB1CXCL12RXRARXRBKDM4E | |
| SCHEMBL10456973 | 0.77 | CYP3A4 (0.47) | HMGB1CXCL12PTGS1PTGS2RXRA | |
| SCHEMBL28090896 | 0.77 | HMGB1 (0.57) | HMGB1CXCL12RXRARXRBALDH1A1 | |
| SCHEMBL4640044 | 0.77 | HMGB1 (0.45) | HMGB1CXCL12RXRARXRBKDM4E | |
| SCHEMBL28733611 | 0.76 | KDM4E (0.41) | HMGB1CXCL12KDM4EMEN1KMT2A | |
| SCHEMBL13652492 | 0.76 | ALDH1A1 (0.50) | HMGB1CXCL12RXRARXRBKDM4E | |
| SCHEMBL2343149 | 0.76 | ALDH1A1 (0.55) | HMGB1CXCL12RXRARXRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057169-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |