Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.33 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.33 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640084 | 0.83 | KDM4E (0.39) | HMGB1CXCL12KDM4EALDH1A1HPGD | |
| SCHEMBL4641134 | 0.81 | TSHR (0.41) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7170533 | 0.79 | KDM4E (0.44) | HMGB1CXCL12KDM4EMEN1KMT2A | |
| SCHEMBL27816873 | 0.77 | HMGB1 (0.52) | HMGB1CXCL12KDM4EMEN1KMT2A | |
| SCHEMBL28960438 | 0.77 | HMGB1 (0.52) | HMGB1CXCL12KDM4EMEN1KMT2A | |
| SCHEMBL674118 | 0.70 | ESR1 (0.50) | HMGB1CXCL12MEN1KMT2AALDH1A1 | |
| SCHEMBL90325 | 0.69 | KDM4E (0.70) | HMGB1CXCL12KDM4EMEN1KMT2A | |
| SCHEMBL4644056 | 0.68 | CYP3A4 (0.46) | KDM4ETDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1259082 | 0.68 | KDM4E (0.63) | HMGB1CXCL12KDM4EMEN1KMT2A | |
| SCHEMBL4643313 | 0.67 | CYP3A4 (0.50) | KDM4ETDP1ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120391-B1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6566548-B1 | Alkylene- or phenylene- tetrabenzoic acids and derivatives | NIPPON SODA CO., LTD. (JP) | 2003-05-20 | — | — | US | disclosed |
| EP-1120391-A1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO., LTD. (JP) | 2001-08-01 | — | — | EP | disclosed |