Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CDC7 | O00311 | 2/20 | 0.53 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299752 | 0.89 | ALDH1A1 (0.60) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL289681 | 0.84 | KDM4E (0.56) | ALDH1A1KDM4ERAB9AL3MBTL1KMT2A | |
| SCHEMBL289676 | 0.81 | KDM4E (0.57) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL290278 | 0.81 | KDM4E (0.66) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL3827647 | 0.81 | KDM4E (0.69) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL289156 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL289582 | 0.80 | RAB9A (0.57) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL290101 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL289161 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ERAB9ACDC7DBF4 | |
| SCHEMBL288534 | 0.79 | KDM4E (0.86) | ALDH1A1KDM4ERAB9ACDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |