Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | HPD | P32754 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 2/20 | 0.50 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149472 | 1.00 | POLB (0.71) | POLBHRH3KCNH2HPDL3MBTL1 | |
| SCHEMBL28961933 | 0.89 | POLB (0.60) | POLBHRH3KCNH2HPDL3MBTL1 | |
| SCHEMBL29110427 | 0.88 | POLB (0.73) | POLBHRH3KCNH2HPDL3MBTL1 | |
| SCHEMBL30089869 | 0.88 | POLB (0.73) | POLBHRH3KCNH2HPDL3MBTL1 | |
| SCHEMBL22238067 | 0.87 | POLB (0.72) | POLBHRH3KCNH2HPDL3MBTL1 | |
| SCHEMBL8307781 | 0.86 | POLB (0.71) | POLBHRH3KCNH2HPDL3MBTL1 | |
| SCHEMBL28924733 | 0.86 | POLB (0.75) | POLBHRH3KCNH2HPDNPC1 | |
| SCHEMBL18332822 | 0.82 | POLB (0.65) | POLBHRH3KCNH2HPDL3MBTL1 | |
| SCHEMBL28924705 | 0.82 | HRH3 (0.62) | POLBHRH3KCNH2HPDNPC1 | |
| SCHEMBL28924692 | 0.81 | POLB (0.50) | POLBHRH3KCNH2HPDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521261-B | Preparation method of mercapto-containing quinazolinone and composition thereof, and application of mercapto-containing quinazolinone in resisting kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-115636795-B | Preparation method of quinazolinone derivative containing thiobenzamide structure and composition thereof, and application of quinazolinone derivative and composition thereof in preventing and treating kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-115636795-A | Quinazolinone derivative containing thiobenzamide structure, composition and application of quinazolinone derivative in prevention and treatment of kiwifruit canker | 贵州理工学院 | 2023-01-24 | — | — | CN | disclosed |
| CN-115521261-A | Preparation method of sulfhydryl-containing quinazolinone and composition thereof and application of sulfhydryl-containing quinazolinone in resisting kiwifruit canker | 贵州理工学院 | 2022-12-27 | — | — | CN | disclosed |