Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 2/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29745940 | 0.86 | MPL (0.58) | MPLEP300HSP90AA1MAPTCA1 | |
| SCHEMBL8428510 | 0.79 | MPL (0.54) | MPLEP300HSP90AA1MAPTALDH1A1 | |
| SCHEMBL9296347 | 0.77 | HSP90AA1 (0.57) | MPLHSP90AA1MAPTCA1TP53 | |
| SCHEMBL7622167 | 0.76 | EP300 (0.56) | EP300HSP90AA1MAPTCA1CA2 | |
| SCHEMBL17765084 | 0.74 | EP300 (0.55) | EP300MAPTCA1CA2TP53 | |
| SCHEMBL10667890 | 0.73 | HSP90AA1 (0.49) | MPLHSP90AA1MAPTCYP3A4HSD17B10 | |
| SCHEMBL28964140 | 0.73 | EP300 (0.73) | EP300HSP90AA1MAPTCA1CA2 | |
| SCHEMBL28917083 | 0.73 | EP300 (0.53) | EP300HSP90AA1MAPTCA1CA2 | |
| SCHEMBL29708049 | 0.72 | ERN1 (0.53) | MPLEP300MAPTCA1CA2 | |
| SCHEMBL1002684 | 0.72 | ERN1 (0.53) | MPLEP300MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433062-B | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-115433062-A | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115433062-B | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-115433062-B | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-115433062-A | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115433062-A | Preparation method and application of 4-methoxy-2-naphthol | 阜阳欣奕华制药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |