Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | MPL | P40238 | 4/20 | 0.54 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179359 | 0.80 | HSP90AA1 (0.50) | HSP90AA1MPLLMNAHTTGRIN2D | |
| SCHEMBL11427080 | 0.79 | THRB (0.62) | HSP90AA1MPLTHRBHTTMEN1 | |
| SCHEMBL11414287 | 0.79 | THRB (0.53) | HSP90AA1MPLTHRBHTTMEN1 | |
| SCHEMBL11413974 | 0.79 | MPL (0.69) | HSP90AA1MPLTRPM4NSD2LDHA | |
| SCHEMBL11330226 | 0.77 | MPL (0.71) | HSP90AA1MPLNSD2CTRC | |
| SCHEMBL29745940 | 0.77 | MPL (0.58) | HSP90AA1MPLLMNAHTTMEN1 | |
| SCHEMBL28964141 | 0.77 | MPL (0.51) | HSP90AA1MPLLMNAMEN1MAPT | |
| SCHEMBL11414363 | 0.77 | MPL (0.67) | HSP90AA1MPLNSD2LDHACTRC | |
| SCHEMBL28693498 | 0.77 | HSP90AA1 (0.47) | HSP90AA1MPLLMNAHTTGRIN2D | |
| SCHEMBL11419689 | 0.76 | KDM4E (0.52) | HSP90AA1MPLTRPM4IDO1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304645-A | Colored or fluorescent labels | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-4954630-A | COLORIMETRIC OR FLUORESCENT ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0209875-B1 | RESORUFIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0209875-A1 | Resorufin derivatives and process for their preparation | Roche Diagnostics GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |