Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668807 | 0.80 | THRB (0.61) | MPLTHRBMEN1KMT2AMAPT | |
| SCHEMBL6668655 | 0.80 | THRB (0.61) | MPLTHRBMEN1KMT2AMAPT | |
| SCHEMBL28964141 | 0.79 | MPL (0.51) | MPLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6666447 | 0.78 | THRB (0.59) | MPLTHRBMEN1KMT2AMAPT | |
| SCHEMBL6666444 | 0.78 | THRB (0.59) | MPLTHRBMEN1KMT2AMAPT | |
| SCHEMBL9634981 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9634986 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL6667583 | 0.77 | KCNH2 (0.48) | THRBMEN1KMT2AMAPTLMNA | |
| SCHEMBL6667586 | 0.77 | KCNH2 (0.48) | THRBMEN1KMT2AMAPTLMNA | |
| SCHEMBL8430279 | 0.76 | THRB (0.56) | MPLTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874547-A | REACTING A PRIMARY AROMATIC AMINE WITH DIAZOTIZING AGENT IN SOLUTION; AZO DYES | CROMPTON & KNOWLES CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |