Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301281 | 1.00 | MAPT (0.59) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL9702101 | 0.86 | MAPT (0.57) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL169696 | 0.85 | MAPT (0.72) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL8345852 | 0.85 | MAPT (0.72) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL13636688 | 0.83 | MAPT (0.65) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL28392967 | 0.82 | HTT (0.62) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL10267340 | 0.81 | MAPT (0.68) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL9702551 | 0.79 | MAPT (0.50) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL1844199 | 0.77 | MAPT (0.82) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL10055019 | 0.77 | MAPT (0.82) | MAPTGAAKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745808-B | Method for preparing secondary amine compound by catalyzing reduction of imine compound | 延安大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115745808-A | Method for preparing secondary amine compound by catalyzing reduction of imine compound | 延安大学 | 2023-03-07 | — | — | CN | disclosed |