Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437396 | 0.90 | NPC1 (0.65) | MAPTGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL13451639 | 0.84 | PPARG (0.63) | MAPTGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL28392967 | 0.83 | HTT (0.62) | MAPTGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL20036943 | 0.83 | INSR (0.75) | ALDH1A1NPC1RAB9AHIF1AFFAR1 | |
| SCHEMBL29606754 | 0.83 | FFAR1 (0.67) | MAPTMEN1KMT2AFFAR1CYP1A2 | |
| SCHEMBL9093298 | 0.83 | FFAR1 (0.67) | MAPTMEN1KMT2AFFAR1CYP1A2 | |
| SCHEMBL28964166 | 0.83 | MAPT (0.59) | MAPTGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL30301281 | 0.83 | MAPT (0.59) | MAPTGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL1844199 | 0.82 | MAPT (0.82) | MAPTGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL10055019 | 0.82 | MAPT (0.82) | MAPTGAAALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931060-B1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2009-11-25 | — | — | EP | disclosed |