SCHEMBL28964246

SCHEMBL28964246

C=C(C)C(=O)OCCNCCl

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.32
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321905 0.88 THRB (0.55) THRBTSHRALDH1A1TDP1POLB
SCHEMBL13950019 0.86 THRB (0.53) THRBTSHRALDH1A1TDP1POLB
SCHEMBL110870 0.82 THRB (0.55) THRBTSHRALDH1A1TDP1POLB
SCHEMBL5576921 0.82 THRB (0.50) THRBTSHRALDH1A1TDP1POLB
SCHEMBL1104076 0.82 THRB (0.47) THRBTSHRALDH1A1TDP1POLB
SCHEMBL14712313 0.82 THRB (0.53) THRBTSHRALDH1A1TDP1POLB
SCHEMBL278238 0.81 THRB (0.46) THRBTSHRALDH1A1TDP1POLB
Hydrochloric Acid SCHEMBL23116684 0.81 THRB (0.53) THRBTSHRALDH1A1TDP1POLB
Bromide SCHEMBL7193814 0.81 THRB (0.53) THRBTSHRALDH1A1TDP1POLB
SCHEMBL11222545 0.81 THRB (0.48) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111107841-B Method for preparing solid dosage forms comprising antibodies by wet granulation, extrusion and spheronization 蒂洛特斯制药股份有限公司 2023-03-10 CN claimed