SCHEMBL278238

SCHEMBL278238

C=CCNCCOC(=O)C(=C)C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.44
KDM4E B2RXH2 6/20 0.39
ALDH1A1 P00352 7/20 0.39
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 2/20 0.38
USP2 O75604 1/20 0.37
GAA P10253 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
APEX1 P27695 1/20 0.35
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2327142 0.85 THRB (0.35) THRBTSHRKDM4EALDH1A1POLB
SCHEMBL9321905 0.85 THRB (0.55) THRBTSHRALDH1A1POLBHTT
SCHEMBL6514445 0.84 THRB (0.39) THRBTSHRKDM4EALDH1A1POLB
SCHEMBL9990498 0.84 THRB (0.44) THRBTSHRALDH1A1POLBHTT
SCHEMBL12332750 0.83 CHRM5 (0.42) TSHRKDM4EALDH1A1POLBSMN1; SMN2
SCHEMBL10977885 0.83 THRB (0.43) THRBTSHRALDH1A1POLBHTT
SCHEMBL13950019 0.83 THRB (0.53) THRBTSHRALDH1A1POLBHTT
SCHEMBL28964246 0.81 THRB (0.48) THRBTSHRALDH1A1POLBHTT
SCHEMBL23031233 0.81 THRB (0.42) THRBTSHRKDM4EALDH1A1POLB
SCHEMBL4945281 0.80 TSHR (0.41) THRBTSHRKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2337554-B1 AGENT FOR FIBRES CONTAINING KERATIN, COMPRISING AT LEAST ONE SPECIFIC AMPHIPHILIC CATIONIC POLYMER AND AT LEAST ONE SPECIFIC, ADDITIONAL FILM-FORMING ANIONIC AND/OR STABILIZING ANIONIC POLYMER HENKEL AG & CO KGAA (DE) 2016-09-07 EP claimed
US-9206552-B2 Absorbent plastic pigment with improved print density containing and recording sheet containing same INTERNATIONAL PAPER COMPANY (US) 2015-12-08 US claimed
US-8777390-B2 Ink-jet printing system with reduced nozzle clogging HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2014-07-15 US claimed
US-20140166036-A1 TRANSFORMATION MEDIUM FOR MODELS CONTAINING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2014-06-19 US claimed
US-20130215184-A1 ABSORBENT PLASTIC PIGMENT WITH IMPROVED PRINT DENSITY AND RECORDING SHEET CONTAINING SAME INTERNATIONAL PAPER COMPANY (US) 2013-08-22 US claimed
WO-2013122756-A1 ABSORBENT PLASTIC PIGMENT WITH IMPROVED PRINT DENSITY AND RECORDING SHEET CONTAINING SAME INTERNATIONAL PAPER COMPANY (US) 2013-08-22 WO claimed
US-20120207694-A1 AGENT FOR TREATING KERATIN-CONTAINING FIBERS, CONTAINING A NON-IONIC STARCH MODIFIED BY PROPYLENE OXIDE AND AN ANIONIC POLYMER HENKEL AG & CO. KGAA 2012-08-16 US claimed
US-8132907-B2 Image forming method FUJIFILM CORPORATION (JP) 2012-03-13 US claimed
US-20110142781-A1 AGENT FOR FIBERS CONTAINING KERATIN, COMPRISING AT LEAST ONE SPECIFIC AMPHIPHILIC CATIONIC POLYMER AND AT LEAST ONE SPECIFIC, ADDITIONAL FILM-FORMING ANIONIC AND/OR STABILIZING ANIONIC POLYMER HENKEL AG & CO. KGAA (DE) 2011-06-16 US claimed
EP-1586454-B1 Ink-jet printing methods and systems providing improved image durability HEWLETT PACKARD DEVELOPMENT CO (US) 2010-03-03 EP claimed
US-20050206705-A1 Ink-jet imaging on offset media HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-09-22 US claimed
US-6779884-B1 Ink-jet printing methods and systems providing dry rub resistance HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-08-24 US claimed
US-20040063808-A1 Ink-jet printing methods and systems providing improved image durability HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-04-01 US claimed
EP-1403346-A1 Ink-jet printing methods and systems providing improved image durability Hewlett-Packard Development Company, L.P. (US) 2004-03-31 EP claimed
US-6423461-B1 INORGANIC POLYMER AND ORGANOMETALLIC POLYMER BLEND OF POLYFERROCENES AND POLYPHOSPHAZENES XEROX CORPORATION 2002-07-23 US claimed
US-6037091-A Carrier with ferrocene containing polymer XEROX CORPORATION (US) 2000-03-14 US claimed
US-6004712-A CORE AND THEREOVER A POLYMER OF (1) METHYLMETHACRYLATE AND A MONOALKYL AMINOALKYL METHACRYLATE, OR (2) A POLYMER OF METHYLMETHACRYLATE AND DIALKYLAMINOALKYL METHACRYLATE, TONER AND DEVELOPER XEROX CORPORATION (US) 1999-12-21 US claimed
US-5574548-A Method and device for developing with a liquid MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1996-11-12 US claimed
US-4212782-A Polymers of acid addition salts of methacrylic acid and a 2-mono(lower)alkylaminoethyl methacrylate NORMAC, INC. (US) 1980-07-15 US claimed
US-3950398-A Methacrylic acid addition salt of 2-mono(lower)alkyl amino ethyl methacrylate NORMAC, INC. (US) 1976-04-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110142781-A1 AGENT FOR FIBERS CONTAINING KERATIN, COMPRISING AT LEAST ONE SPECIFIC AMPHIPHILIC CATIONIC POLYMER AND AT LEAST ONE SPECIFIC, ADDITIONAL FILM-FORMING ANIONIC AND/OR STABILIZING ANIONIC POLYMER KRT18, H1-10, C9 THRB 2878/4885TSHR 1658/4885KDM4E 168/4885
US-20120207694-A1 AGENT FOR TREATING KERATIN-CONTAINING FIBERS, CONTAINING A NON-IONIC STARCH MODIFIED BY PROPYLENE OXIDE AND AN ANIONIC POLYMER KRT18, F12, H1-10 THRB 2114/4885TSHR 1436/4885KDM4E 2089/4885
US-20140166036-A1 TRANSFORMATION MEDIUM FOR MODELS CONTAINING KERATIN FIBERS KRT18, NEFM, CUTA THRB 3694/4885TSHR 1366/4885KDM4E 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.