Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17238089 | 0.98 | ALDH1A1 (0.40) | ALDH1A1TP53MAPK10MEN1KMT2A | |
| SCHEMBL23930587 | 0.98 | ALDH1A1 (0.40) | ALDH1A1TP53MAPK10MEN1KMT2A | |
| SCHEMBL5949813 | 0.81 | SIGMAR1 (0.41) | TP53IDO1 | |
| SCHEMBL5949807 | 0.81 | SIGMAR1 (0.41) | TP53IDO1 | |
| SCHEMBL19673833 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TP53MEN1KMT2ALMNA | |
| SCHEMBL16014418 | 0.80 | CNR1 (0.39) | ALDH1A1TP53MEN1KMT2ARAB9A | |
| SCHEMBL17238111 | 0.80 | TDP1 (0.41) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL17238096 | 0.80 | MAPT (0.45) | ALDH1A1TP53MEN1KMT2ALMNA | |
| SCHEMBL21313128 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TP53MEN1KMT2ALMNA | |
| SCHEMBL17238103 | 0.78 | MEN1 (0.46) | ALDH1A1MAPK10MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697979-A | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2023-02-03 | — | — | CN | disclosed |