Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28803626 | 1.00 | ALDH1A1 (0.55) | ALDH1A1FFAR3LCKFYNTDP1 | |
| SCHEMBL28170047 | 0.94 | ALDH1A1 (0.61) | ALDH1A1FFAR3LCKFYNTDP1 | |
| SCHEMBL15963 | 0.94 | ALDH1A1 (0.61) | ALDH1A1FFAR3LCKFYNTDP1 | |
| Methacrylic Acid SCHEMBL4305464 | 0.91 | ALDH1A1 (0.52) | ALDH1A1FFAR3LCKFYNTDP1 | |
| Oxalic Acid SCHEMBL28217950 | 0.91 | ALDH1A1 (0.52) | ALDH1A1FFAR3LCKFYNTDP1 | |
| SCHEMBL8953021 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TDP1HSD17B10TSHRTHRB | |
| Hydrochloric Acid SCHEMBL17099626 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TDP1HSD17B10TSHRTHRB | |
| SCHEMBL31589203 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TDP1HSD17B10TSHRTHRB | |
| SCHEMBL31415277 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TDP1HSD17B10TSHRTHRB | |
| SCHEMBL31462280 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TDP1HSD17B10TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705136-B2 | Synthesis of 3′-, or 5′-, or internal methacrylamido-modified oligonucleotides | UCHICAGO ARGONNE, LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-20060194213-A1 | Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides | U CHICAGO ARGONNE LLC | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194213-A1 | Synthesis of 3'-, or 5'-, or internal methacrylamido-modified oligonucleotides | NSUN2, RNGTT, BCDIN3D | ALDH1A1 2022/4885FFAR3 3342/4885LCK 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.