SCHEMBL2896530

SCHEMBL2896530

O=C(OC1CC2C=CC1C2)c1cccc(-c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.43
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
FFAR4 Q5NUL3 1/20 0.39
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
ERCC5 P28715 1/20 0.38
FEN1 P39748 1/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2839505 0.88 SCN1A (0.47) MAPTCHRM2CHRM4CHRM1CHRM3
SCHEMBL2899524 0.87 CHRM2 (0.47) CHRM2CHRM4CHRM1CHRM3
SCHEMBL2899217 0.80 SCN1A (0.49)
SCHEMBL2898584 0.80 BCHE (0.45) MAPTTDP1NPC1RAB9A
SCHEMBL12692038 0.80 POLB (0.40) CHRM2CHRM4CHRM1CHRM3
SCHEMBL203002 0.79 FFAR4 (0.44) KMOMAPTTDP1FFAR4NPC1
SCHEMBL6475721 0.78 SRD5A2 (0.40) MAPTCHRM2CHRM4CHRM1CHRM3
SCHEMBL201540 0.77 PDCD1 (0.41) KMOMAPTTDP1HDAC8FFAR4
SCHEMBL201541 0.77 NPC1 (0.41) KMOMAPTTDP1FFAR4NPC1
SCHEMBL14002248 0.76 MEN1 (0.43) CHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
US-7101498-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US disclosed
US-6846890-B2 Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040242824-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING OPENING POLYMERIZATION JSR CORPORATION (JP) 2004-12-02 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1459107-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-09-22 EP disclosed
EP-1435350-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING-OPENING POLYMERIZATION JSR Corporation (JP) 2004-07-07 EP disclosed
WO-2003056365-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2003-07-10 WO disclosed