SCHEMBL2899524

SCHEMBL2899524

O=C(OC1CC2C=CC1C2)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.47
CHRM4 P08173 2/20 0.47
CHRM1 P11229 2/20 0.47
CHRM3 P20309 2/20 0.47
CHRNA7 P36544 2/20 0.45
HTR3E A5X5Y0 2/20 0.43
HTR3B O95264 2/20 0.43
HTR3A P46098 2/20 0.43
HTR3D Q70Z44 2/20 0.43
HTR3C Q8WXA8 2/20 0.43
BCHE P06276 1/20 0.43
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12692038 0.92 POLB (0.40) CHRM2CHRM4CHRM1CHRM3CHRNA7
SCHEMBL2839505 0.91 SCN1A (0.47) CHRM2CHRM4CHRM1CHRM3CHRNA7
SCHEMBL2896530 0.87 KMO (0.43) CHRM2CHRM4CHRM1CHRM3
SCHEMBL2898584 0.83 BCHE (0.45) BCHE
SCHEMBL2899217 0.83 SCN1A (0.49)
SCHEMBL4401228 0.81 KMT2A (0.40)
SCHEMBL6475721 0.81 SRD5A2 (0.40) CHRM2CHRM4CHRM1CHRM3
SCHEMBL14002248 0.79 MEN1 (0.43) CHRM2CHRM4CHRM1CHRM3BCHE
SCHEMBL6481509 0.79 SRD5A2 (0.45)
SCHEMBL2896264 0.79 SRD5A2 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS, PBC 2025-10-09 US disclosed
EP-2094760-B1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 3M INNOVATIVE PROPERTIES CO (US) 2017-05-31 EP disclosed
EP-1884519-B1 METAL HYDRIDE COMPLEX, METHOD OF HYDROGENATING RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN, AND PROCESS FOR PRODUCING PRODUCT OF HYDROGENATION OF RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN JSR CORP (JP) 2014-03-19 EP disclosed
US-8431625-B2 Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-30 US disclosed
US-8431625-B2 Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-30 US disclosed
US-8178604-B2 Solid materials obtainable by ring-opening metathesis polymerization 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
US-8178604-B2 Solid materials obtainable by ring-opening metathesis polymerization 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
EP-1815838-B1 Solid materials obtainable by the ring-opening methathesis polymerization 3M INNOVATIVE PROPERTIES CO (US) 2010-09-08 EP disclosed
US-7675587-B2 Polarizing plate and process for producing the same JSR CORPORATION (JP) 2010-03-09 US disclosed
US-20100036015-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 3M INNOVATIVE PROPERTIES COMPANY 2010-02-11 US disclosed
EP-1884519-A1 METAL HYDRIDE COMPLEX, METHOD OF HYDROGENATING RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN, AND PROCESS FOR PRODUCING PRODUCT OF HYDROGENATION OF RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN JSR Corporation (JP) 2008-02-06 EP disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
WO-2007089801-A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-08-09 WO disclosed
EP-1815838-A1 Solid materials obtainable by the ring-opening methathesis polymerization 3M Innovative Properties Company (US) 2007-08-08 EP disclosed
US-7101498-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US disclosed
EP-1626294-A2 Polarizing plate and process for producing the same JSR Corporation (JP) 2006-02-15 EP disclosed
US-20060027322-A1 Polarizing plate and process for producing the same JSR CORPORATION (JP) 2006-02-09 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1459107-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-09-22 EP disclosed
WO-2003056365-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2003-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CYP8B1, CYP1B1, BBOX1 CHRM2 3001/4885CHRM4 3652/4885CHRM1 2336/4885
US-20100036015-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD DNMT3B, HMBS, MMAB CHRM2 2124/4885CHRM4 1660/4885CHRM1 1075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.