SCHEMBL2899217

SCHEMBL2899217

O=C(OC1CC2C=CC1C2)c1ccccc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 4/20 0.49
SCN2A Q99250 4/20 0.49
SCN3A Q9NY46 4/20 0.49
CHRNB2 P17787 7/20 0.43
CHRNA4 P43681 7/20 0.43
CHRNB4 P30926 6/20 0.41
CHRNA3 P32297 6/20 0.41
BCAT2 O15382 1/20 0.41
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 2/20 0.40
GAA P10253 1/20 0.39
TSHR P16473 1/20 0.38
RECQL P46063 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2839505 0.83 SCN1A (0.47) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL2899524 0.83 CHRM2 (0.47)
SCHEMBL2896530 0.80 KMO (0.43)
SCHEMBL6475500 0.79 HTR2B (0.43) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL2899404 0.78 BCHE (0.46) GAAMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL201988 0.78 CHRNB2 (0.56) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL12692038 0.78 POLB (0.40) KMT2AALDH1A1LMNA
SCHEMBL203249 0.76 SCN1A (0.48) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL203248 0.76 SCN1A (0.46) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL6474822 0.75 TRPA1 (0.34) GAATSHRSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
US-7101498-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US disclosed
US-6846890-B2 Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040242824-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING OPENING POLYMERIZATION JSR CORPORATION (JP) 2004-12-02 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1435350-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING-OPENING POLYMERIZATION JSR Corporation (JP) 2004-07-07 EP disclosed