SCHEMBL28965366

SCHEMBL28965366

CC(C)(C)CCNS(=O)(=O)c1nc2ccccc2s1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.51
PSMB5 P28074 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ALDH1A1 P00352 10/20 0.47
LMNA P02545 5/20 0.47
MAPT P10636 5/20 0.47
KMT2A Q03164 5/20 0.47
HTT P42858 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MEN1 O00255 2/20 0.47
SMN1; SMN2 Q16637 4/20 0.43
LOXL2 Q9Y4K0 1/20 0.40
AKR1B1 P15121 1/20 0.40
STAT3 P40763 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883388 0.82 PSMB8 (0.53) PSMB8PSMB5CA12CA1CA2
SCHEMBL31546243 0.82 PSMB8 (0.53) PSMB8PSMB5CA12CA1CA2
SCHEMBL3282188 0.82 PSMB8 (0.55) PSMB8PSMB5CA12CA1CA2
SCHEMBL21873110 0.81 PSMB8 (0.51) PSMB8PSMB5CA12CA1CA2
SCHEMBL27839385 0.80 PSMB8 (0.50) PSMB8PSMB5CA12CA1CA2
SCHEMBL29392184 0.80 PSMB8 (0.60) PSMB8PSMB5CA12CA1CA2
SCHEMBL721698 0.80 PSMB8 (0.60) PSMB8PSMB5CA12CA1CA2
SCHEMBL31635992 0.79 ALDH1A1 (0.59) PSMB8PSMB5CA12CA1CA2
SCHEMBL30903434 0.79 PSMB8 (0.58) PSMB8PSMB5CA12CA1CA2
SCHEMBL8417368 0.79 PSMB8 (0.58) PSMB8PSMB5CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772288-A Flame-retardant insulating sole rubber material and refining process thereof 江苏盾王科技集团有限公司 2023-03-10 CN disclosed