SCHEMBL3282188

SCHEMBL3282188

O=S(=O)(NCCO)c1nc2ccccc2s1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.55
PSMB5 P28074 1/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA7 P43166 1/20 0.54
CA14 Q9ULX7 1/20 0.54
ALDH1A1 P00352 7/20 0.50
MAPT P10636 4/20 0.50
LMNA P02545 3/20 0.50
HTT P42858 3/20 0.50
KMT2A Q03164 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
MEN1 O00255 1/20 0.50
SMN1; SMN2 Q16637 5/20 0.46
AKR1B1 P15121 1/20 0.43
MAPK9 P45984 1/20 0.42
MAPK10 P53779 1/20 0.42
CCNE1 P24864 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883388 0.83 PSMB8 (0.53) PSMB8PSMB5CA12CA1CA2
SCHEMBL31546243 0.83 PSMB8 (0.53) PSMB8PSMB5CA12CA1CA2
SCHEMBL8417368 0.82 PSMB8 (0.58) PSMB8PSMB5CA12CA1CA2
SCHEMBL28965366 0.82 PSMB8 (0.51) PSMB8PSMB5CA12CA1CA2
SCHEMBL21873110 0.82 PSMB8 (0.51) PSMB8PSMB5CA12CA1CA2
SCHEMBL3132766 0.81 CA1 (0.51) PSMB8PSMB5CA12CA1CA2
SCHEMBL27839385 0.81 PSMB8 (0.50) PSMB8PSMB5CA12CA1CA2
SCHEMBL5329554 0.81 PSMB8 (0.57) PSMB8PSMB5CA12CA1CA2
SCHEMBL8799542 0.80 CA1 (0.55) PSMB8PSMB5CA12CA1CA2
SCHEMBL8229512 0.80 PSMB8 (0.64) PSMB8PSMB5CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850273-B2 CALENDERED ELASTOMERIC ARTICLES EXXONMOBIL CHEM PATENTS INC (US) 2010-06-30 EP disclosed
US-7629416-B2 Plasticized polyolefin compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-12-08 US disclosed
US-20080227919-A9 blends of high-melting polypropylene polymers, low-crystallinity polypropylene polymers and non-functionalized plasticizers, having improved balance of heat resistance, softness, toughness and/or elasticity LI WEN 2008-09-18 US disclosed
EP-1893686-A1 PLASTICIZED POLYOLEFIN COMPOSITIONS ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2008-03-05 EP disclosed
US-7175167-B2 Elastomeric suspension spring for a motor vehicle and a suspension joint incorporating the spring MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2007-02-13 US disclosed
WO-2006118674-A1 PLASTICIZED POLYOLEFIN COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-11-09 WO disclosed
US-20060135699-A1 blends of high-melting polypropylene polymers, low-crystallinity polypropylene polymers and non-functionalized plasticizers, having improved balance of heat resistance, softness, toughness and/or elasticity EXXONMOBIL CHEMICAL PATENTS INC. 2006-06-22 US disclosed
US-20040102567-A1 Elastomeric suspension spring for a motor vehicle and a suspension joint incorporating the spring MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2004-05-27 US disclosed
EP-1404758-A1 ELASTOMERIC SUSPENSION SPRING FOR MOTOR VEHICLE AND ARTICULATION INCORPORATING SAME Société de Technologie Michelin (FR) 2004-04-07 EP disclosed
WO-2002094931-A1 ELASTOMERIC SUSPENSION SPRING FOR MOTOR VEHICLE AND ARTICULATION INCORPORATING SAME SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2002-11-28 WO disclosed
EP-0850273-B1 CALENDERED ELASTOMERIC ARTICLES EXXON CHEMICAL PATENTS INC (US) 2000-01-05 EP disclosed
US-5654370-A ROOFING SHEETS EXXON CHEMICAL PATENTS INC. (US) 1997-08-05 US disclosed
US-5571868-A BLENDS OF ETHYLENE, ALPHA-OLEFIN, NON-CONJUGATED BICYCLIC DIENE POLYMERS; HIGH GREEN STRENGTH, PEEL ADHESION; ROOFING EXXON CHEMICAL PATENTS INC. (US) 1996-11-05 US disclosed