Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Lactic Acid SCHEMBL30797074 | 0.92 | TP53 (0.52) | TP53TSHRHSD17B10MGAMGAA | |
| Propionic Acid SCHEMBL29156531 | 0.89 | FFAR3 (0.37) | TP53FFAR3TSHRHSD17B10MGAM | |
| Propionic Acid SCHEMBL30697043 | 0.87 | FFAR3 (0.53) | FFAR3TSHRHSD17B10MGAMGAA | |
| Lactic Acid SCHEMBL28965405 | 0.87 | FFAR3 (0.46) | TP53FFAR3TSHRHSD17B10SLC1A1 | |
| Lactic Acid SCHEMBL28965389 | 0.83 | TP53 (0.58) | TP53FFAR3TSHRCYP1A2OR51E2 | |
| Lactic Acid SCHEMBL28965397 | 0.82 | TP53 (0.42) | TP53FFAR3HSD17B10MGAMGAA | |
| Lactic Acid SCHEMBL288873 | 0.80 | TP53 (0.69) | TP53FFAR3CYP1A2 | |
| Lactic Acid SCHEMBL28371979 | 0.80 | TP53 (0.69) | TP53FFAR3CYP1A2 | |
| Glycolic Acid SCHEMBL28382388 | 0.78 | TSHR (0.50) | FFAR3TSHRHSD17B10MGAMGAA | |
| Propionic Acid SCHEMBL28965378 | 0.78 | FFAR3 (0.42) | TP53FFAR3TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745946-A | Low-temperature preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-03-07 | — | — | CN | disclosed |