Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | YWHAG | P61981 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611761 | 0.98 | KDM4E (0.58) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL28965417 | 0.84 | ALDH1A1 (0.58) | KDM4ERAB9AALDH1A1GAAMAPT | |
| SCHEMBL112686 | 0.82 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2ALDH1A1MAPTTHRB | |
| SCHEMBL28965486 | 0.81 | ALDH1A1 (0.57) | KDM4ESMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL14226901 | 0.81 | KDM4E (0.58) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL10261801 | 0.81 | HTT (0.68) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL17478975 | 0.81 | ALDH1A1 (0.62) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL28353635 | 0.80 | KDM4E (0.54) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL23611740 | 0.80 | ALDH1A1 (0.60) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29930952 | 0.80 | ALDH1A1 (0.60) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745874-A | Preparation method of o-pyrrolidinyl benzamide compound | 南华大学附属第一医院 | 2023-03-07 | — | — | CN | disclosed |