Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | YWHAG | P61981 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930952 | 0.98 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL23611740 | 0.98 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL20141454 | 0.85 | LMNA (0.50) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL17478873 | 0.85 | GAA (0.65) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL29239530 | 0.85 | GAA (0.46) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL29805092 | 0.85 | LMNA (0.50) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL28965421 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL3825337 | 0.85 | GAA (0.50) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL3828922 | 0.84 | KDM4E (0.46) | ALDH1A1SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL28965451 | 0.81 | KDM4E (0.56) | ALDH1A1SMN1; SMN2GAAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745874-A | Preparation method of o-pyrrolidinyl benzamide compound | 南华大学附属第一医院 | 2023-03-07 | — | — | CN | disclosed |