Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465716 | 0.81 | CYP2D6 (0.34) | CYP2D6KCNH2HRH3HSD11B1 | |
| SCHEMBL4475027 | 0.78 | HSD17B10 (0.39) | CYP2D6 | |
| SCHEMBL4476428 | 0.77 | CYP2D6 (0.38) | CYP2D6KCNH2HRH3HSD11B1 | |
| SCHEMBL485135 | 0.71 | ALOX5 (0.45) | — | |
| SCHEMBL28473191 | 0.70 | DPP4 (0.31) | CYP2D6KCNH2HRH3ARG1ARG2 | |
| SCHEMBL5765556 | 0.69 | CYP2D6 (0.55) | CYP2D6KCNH2HRH3HSD11B1 | |
| SCHEMBL28405167 | 0.69 | LMNA (0.36) | CYP2D6KCNH2HRH3HSD11B1 | |
| SCHEMBL28703415 | 0.69 | PAOX (0.35) | CYP2D6KCNH2HRH3HSD11B1 | |
| SCHEMBL1698890 | 0.68 | TACR3 (0.40) | ARG1ARG2 | |
| SCHEMBL3430000 | 0.68 | TACR3 (0.40) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605267-A | Selective modulators of mutant LRRK2 proteolysis and related methods of use | 阿维纳斯企业公司（US） | 2023-01-13 | — | — | CN | disclosed |