Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965660 | 0.78 | CA12 (0.38) | RXFP1CA12CA1CA9RORC | |
| SCHEMBL28965760 | 0.77 | P2RX4 (0.38) | P2RX4 | |
| SCHEMBL28965582 | 0.76 | P2RX4 (0.37) | P2RX4 | |
| SCHEMBL29075988 | 0.76 | RECQL (0.40) | P2RX7RXFP1P2RX4HPGD | |
| Hydrochloric Acid SCHEMBL28965723 | 0.76 | P2RX4 (0.37) | P2RX4 | |
| SCHEMBL28965746 | 0.76 | DDB1 (0.33) | CASP1DDB1CRBN | |
| SCHEMBL28965671 | 0.72 | P2RX4 (0.44) | P2RX4HPGD | |
| SCHEMBL13587071 | 0.68 | CA12 (0.42) | ELANECTRB1BRD9CYP17A1RXFP1 | |
| SCHEMBL3041905 | 0.67 | GAA (0.46) | ELANECTRB1BRD9CYP17A1RXFP1 | |
| SCHEMBL27297 | 0.66 | P2RX7 (0.48) | P2RX7BRD9RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-B | Substituted tricyclic compounds | 鲁宾有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-116723843-A | Pharmaceutical combination of SOS1 inhibitors for the treatment and/or prevention of cancer | 鲁宾有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |