Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965760 | 0.79 | P2RX4 (0.38) | P2RX4BCHEPKMKDM4EABHD10 | |
| SCHEMBL29075988 | 0.78 | RECQL (0.40) | P2RX4BCHEALDH1A1KDM4EHPGD | |
| SCHEMBL29267745 | 0.78 | KDM4E (0.35) | P2RX4BCHEPKMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28965723 | 0.78 | P2RX4 (0.37) | P2RX4BCHEPKMABHD10ATM | |
| SCHEMBL28965582 | 0.78 | P2RX4 (0.37) | P2RX4BCHEALDH1A1ABHD10ATM | |
| SCHEMBL29267728 | 0.78 | P2RX4 (0.32) | P2RX4BCHEABHD10ATM | |
| SCHEMBL28050747 | 0.72 | OPRM1 (0.44) | TP53ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL28965657 | 0.72 | ELANE (0.35) | P2RX4HPGD | |
| SCHEMBL28965660 | 0.71 | CA12 (0.38) | — | |
| SCHEMBL3072283 | 0.69 | P2RX4 (0.60) | P2RX4BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-B | Substituted tricyclic compounds | 鲁宾有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |