SCHEMBL28966366

SCHEMBL28966366

O=[N+]([O-])c1ccc2c(cc(O)c3c4ccccc4ccc23)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.54
CASP6 P55212 1/20 0.50
CDK2 P24941 2/20 0.48
CTSB P07858 1/20 0.46
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MAPT P10636 4/20 0.42
KDM4E B2RXH2 2/20 0.42
APAF1 O14727 1/20 0.42
ATM Q13315 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
HPGD P15428 2/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28058443 0.82 CASP6 (0.66) HPRT1CASP6CTSBALDH1A1MEN1
SCHEMBL589016 0.82 CASP6 (0.66) HPRT1CASP6CTSBALDH1A1MEN1
SCHEMBL11407415 0.80 CASP6 (0.64) HPRT1CASP6CTSBALDH1A1MEN1
Hydrogen Sulfide SCHEMBL28182398 0.80 CASP6 (0.64) HPRT1CASP6CTSBALDH1A1MEN1
Methyl Alcohol SCHEMBL28580666 0.79 CASP6 (0.62) HPRT1CASP6CTSBALDH1A1MEN1
SCHEMBL31235726 0.77 HPRT1 (0.56) HPRT1ALDH1A1RAB9AMAPTATM
Alcohol SCHEMBL28601219 0.75 CASP6 (0.57) HPRT1CASP6CTSBALDH1A1MEN1
SCHEMBL348055 0.72 HPRT1 (0.67) HPRT1CASP6CDK2CTSBALDH1A1
SCHEMBL25622486 0.71 TRPM4 (0.59) HPRT1ALDH1A1RAB9AMAPTATM
SCHEMBL27760500 0.71 TRPM4 (0.65) HPRT1ALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115769059-A Computer-implemented method, computer program product and system for data analysis 赛多利斯司特蒂姆数据分析公司 2023-03-07 CN disclosed