Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28580666 | 0.92 | CASP6 (0.62) | CASP6ALDH1A1HPRT1CTSBTNF | |
| SCHEMBL28058443 | 0.92 | CASP6 (0.66) | CASP6ALDH1A1HPRT1CTSBTNF | |
| SCHEMBL589016 | 0.92 | CASP6 (0.66) | CASP6ALDH1A1HPRT1CTSBTNF | |
| SCHEMBL11407415 | 0.90 | CASP6 (0.64) | CASP6ALDH1A1HPRT1CTSBTNF | |
| Hydrogen Sulfide SCHEMBL28182398 | 0.90 | CASP6 (0.64) | CASP6ALDH1A1HPRT1CTSBTNF | |
| Alcohol SCHEMBL27961237 | 0.81 | ALDH1A1 (0.79) | CASP6ALDH1A1HPRT1CTSBGPR35 | |
| SCHEMBL8671636 | 0.77 | ALDH1A1 (0.55) | CASP6ALDH1A1HPRT1CTSBTNF | |
| SCHEMBL28966366 | 0.75 | HPRT1 (0.54) | CASP6ALDH1A1HPRT1CTSBTNF | |
| Alcohol SCHEMBL27548373 | 0.74 | HSD17B10 (0.58) | ALDH1A1GPR35MEN1KMT2ATSHR | |
| SCHEMBL7801282 | 0.74 | ALDH1A1 (0.51) | CASP6ALDH1A1HPRT1CTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113030073-B | Method for extracting, showing and verifying copper and lead residues in bullet traces | 公安部物证鉴定中心 | 2022-11-01 | — | — | CN | claimed |
| CN-113030073-A | Method for extracting, showing and verifying copper and lead residues in bullet traces | 公安部物证鉴定中心 | 2021-06-25 | — | — | CN | claimed |
| CN-113030073-B | Method for extracting, showing and verifying copper and lead residues in bullet traces | 公安部物证鉴定中心 | 2022-11-01 | — | — | CN | disclosed |
| CN-113030073-A | Method for extracting, showing and verifying copper and lead residues in bullet traces | 公安部物证鉴定中心 | 2021-06-25 | — | — | CN | disclosed |