Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17690718 | 0.90 | NPSR1 (0.57) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL9844038 | 0.85 | ALDH1A1 (0.60) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL28845306 | 0.85 | TSHR (0.64) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL9843976 | 0.81 | NPSR1 (0.77) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL14263838 | 0.79 | TSHR (0.66) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL9844424 | 0.79 | NPSR1 (0.56) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL22525971 | 0.77 | NPSR1 (0.55) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL27935595 | 0.77 | NPSR1 (0.55) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL9754281 | 0.77 | TSHR (0.62) | TSHRALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL5834057 | 0.77 | TSHR (0.62) | TSHRALDH1A1KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |