Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844158 | 0.84 | TSHR (0.59) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL28845306 | 0.84 | TSHR (0.64) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9844038 | 0.84 | ALDH1A1 (0.60) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5834057 | 0.83 | TSHR (0.62) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL14263838 | 0.82 | TSHR (0.66) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4184595 | 0.82 | TSHR (0.61) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5148694 | 0.82 | TSHR (0.61) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL6289427 | 0.82 | TSHR (0.61) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4665022 | 0.82 | ALDH1A1 (0.62) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9844424 | 0.81 | NPSR1 (0.56) | TSHRKMT2AALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015464-A1 | AMIDE ESTER ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-10-17 | — | — | WO | claimed |
| WO-1991015464-A1 | AMIDE ESTER ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-10-17 | — | — | WO | disclosed |