Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40778 | 0.83 | CMA1 (0.66) | GSK3AGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL16429902 | 0.81 | KMT2A (0.64) | GSK3AGSK3BHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL31175413 | 0.81 | GSK3A (0.53) | GSK3AGSK3BHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL10195154 | 0.81 | GSK3A (0.64) | GSK3AGSK3BHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL22944366 | 0.79 | GSK3A (0.40) | GSK3AGSK3BHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL12615721 | 0.78 | GSK3A (0.60) | GSK3AGSK3BHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL3381344 | 0.78 | GSK3A (1.00) | GSK3AGSK3BHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL17525752 | 0.78 | CA1 (0.40) | GSK3AGSK3BHRH3ALDH1A1CA1 | |
| SCHEMBL9390734 | 0.78 | KMT2A (0.62) | GSK3AGSK3BSIGMAR1ALDH1A1MEN1 | |
| SCHEMBL11432099 | 0.77 | SIGMAR1 (0.60) | GSK3AGSK3BHRH3SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |