Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL8669345 | 0.89 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL8746438 | 0.89 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL11590105 | 0.87 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL28399898 | 0.87 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL30340746 | 0.87 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL31230843 | 0.87 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Dopamine SCHEMBL29724692 | 0.85 | LCK (0.64) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL10630371 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL11512229 | 0.85 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 | |
| Salicylic Acid SCHEMBL27426678 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115607556-A | Medicine for preventing and treating asthma, chronic obstructive pulmonary disease, allergic diseases, etc | 刘力 | 2023-01-17 | — | — | CN | claimed |